Company Filing History:
Years Active: 1996-2016
Title: The Innovations of Charles Phoebe
Introduction
Charles Phoebe is an accomplished inventor based in Uxbridge, MA (US). He holds 2 patents that showcase his expertise in chromatographic technologies and carbohydrate immobilization methods. His work has significantly contributed to advancements in analytical chemistry and biochemistry.
Latest Patents
One of his latest patents is a chromatographic interface designed for sample handling and manipulation between separations or analyses. This innovative interface includes an interfacing unit, a sample acquisition unit, and a sample trapping unit. The sample acquisition unit features an inflow selector valve, an outflow selector valve, and one or more collection loops. The sample trapping unit is equipped with a trap in fluid communication with the loop, which contains a stationary phase capable of trapping an analyte of interest from a fraction of the chromatographic sample separation flow. Additionally, the trapping unit has a scavenging gas source and a vacuum source, both of which can be utilized to substantially dry the stationary phase.
Another significant patent involves a method for covalent immobilization of charge-conjugated carbohydrate molecules. This method includes adsorbing the carbohydrate molecule to an oppositely charged surface in proximity to reactive moieties bound to the charged surface. The process activates the bound moiety sufficiently for covalent attachment to the adsorbed carbohydrate molecule. This patent also discloses a hydrophobic microporous polymer membrane coated with a cross-linked, cationic polymer that has fixed charges, enhancing the epoxide content for covalent immobilization of the oppositely charged carbohydrate molecule.
Career Highlights
Charles Phoebe has worked with notable companies such as Millipore Corporation and Waters Technologies Corporation. His experience in these organizations has allowed him to develop and refine his innovative ideas in the field of chromatography and biochemistry.
Collaborations
Throughout his career, Charles has collaborated with esteemed colleagues, including John Charkoudian and Malcolm G Pluskal. These partnerships have fostered a creative environment that has led to significant advancements in their respective fields.
Conclusion
Charles Phoebe's contributions to the fields of chromatography and carbohydrate chemistry are noteworthy. His innovative patents and collaborations reflect his dedication to advancing scientific knowledge and technology.