Charles C Ditlow

Title: **Innovations by Charles C. Ditlow in Immunoassay Technology**

Introduction

Charles C. Ditlow, an innovative inventor based in Brockton, MA, has made significant contributions to the field of immunoassays. With a total of two patents to his name, Ditlow has focused on enhancing the accuracy and reliability of urine testing, which has wide-ranging applications in medical diagnostics.

Latest Patents

One of his most notable inventions is the "Sol Capture Immunoassay Kit and Procedure." This innovative procedure allows for the detection of analytes in urine through an immunological reaction conducted in an aqueous phase. If the assay is positive, a filterable immunocomposite is formed containing an inherently colored gold sol particle, which can be visually observed on a filter element. To minimize false positive readings, the procedure employs several strategies:

1. Contaminants are removed from the urine to prevent clogging and non-specific binding by using a porous contact element with detergent material.

2. Non-specific binding of unreacted immunoreactive substances is prevented by blocking the filter element with polyvinyl pyrrolidone.

3. A green dye material is included in the aqueous reaction phase to enhance optical distinction between negative and positive results after washing the collection filter.

Career Highlights

Charles C. Ditlow is an integral part of Hygeia Sciences, Inc., where he continues to work on groundbreaking solutions in the field of diagnostics. His innovative spirit and dedicated work in the immunoassay domain have not only advanced laboratory testing methods but have also aimed to improve patient outcomes.

Collaborations

Throughout his career, Ditlow has collaborated with distinguished colleagues such as L. Edward Cannon and Francis X. Cole. These partnerships have fostered an environment of innovation and have contributed to the successful development of his patented technologies.

Conclusion

Charles C. Ditlow stands out as a significant figure in the realm of immunoassays. His inventions, particularly the Sol Capture Immunoassay Kit and Procedure, have revolutionized how urine analytes are detected, offering a more accurate and efficient testing method. As he continues to develop new technologies at Hygeia Sciences, Inc., Ditlow's work will likely have lasting impacts in the field of medical diagnostics.