Years Active: 2014-2024
Title: The Innovations of Charles B Duke
Introduction
Charles B Duke is a prominent inventor based in Memphis, TN, known for his significant contributions to the field of pharmaceuticals. With a total of 13 patents to his name, Duke has made remarkable strides in developing treatments for various medical conditions, particularly those related to androgen receptors.
Latest Patents
Duke's latest patents include innovative compounds known as selective androgen receptor degraders (SARDs). These compounds, which encompass novel indole, indazole, benzimidazole, benzotriazole, indoline, quinolone, isoquinoline, and carbazole structures, are designed to treat hyperproliferations of the prostate, including pre-malignancies, benign prostatic hyperplasia, and prostate cancer. Additionally, he has developed 3-amino propanamide SARD compounds that target similar conditions, including advanced prostate cancer and androgenic alopecia. His inventions aim to reduce the levels and activity of androgen receptors, addressing various diseases such as Kennedy's disease, amyotrophic lateral sclerosis (ALS), and uterine fibroids.
Career Highlights
Throughout his career, Charles B Duke has worked with esteemed organizations, including the University of Tennessee Research Foundation and GTx Corporation. His work has significantly impacted the pharmaceutical industry, particularly in the development of targeted therapies for cancer and other androgen-related conditions.
Collaborations
Duke has collaborated with notable professionals in his field, including James T Dalton and Duane Douglas Miller. These partnerships have contributed to the advancement of his research and the successful development of his patented inventions.
Conclusion
Charles B Duke's innovative work in the realm of selective androgen receptor degraders showcases his dedication to improving medical treatments for serious health conditions. His contributions continue to influence the pharmaceutical landscape, making him a noteworthy figure in the field of invention.
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