Valparaiso, IN, United States of America

Charles Auxilium Francis


Average Co-Inventor Count = 1.7

ph-index = 6

Forward Citations = 174(Granted Patents)


Location History:

  • Oxnard, CA (US) (1990)
  • Valparaiso, IN (US) (2004 - 2006)

Company Filing History:


Years Active: 1990-2006

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6 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Charles Auxilium Francis

Introduction

Charles Auxilium Francis, based in Valparaiso, IN, is a notable inventor recognized for his significant contributions to the field of pharmaceutical manufacturing. With an impressive portfolio of 6 patents, his work primarily revolves around the production of opioid analgesics, further advancing medical science and pain management therapies.

Latest Patents

Among Francis's latest patents are groundbreaking processes that enhance the manufacturing of opioids. One such patent details a method for producing Oxycodone, utilizing a specific composition that includes a thebaine component processed into 14-hydroxycodeinone, followed by its reduction to Oxycodone. This innovative approach not only ensures high yields but also maintains a high purity of the final product.

Another significant patent outlines the process for producing opiates, where a morphine concentrate, such as that derived from poppy straw, is meticulously converted into codeine. This conversion process is characterized by several steps, including the preparation of a morphine solution in an inert solvent, followed by methylation with a suitable agent in the presence of an alkaline ingredient, ultimately leading to the recovery of codeine either as a free base or in salt form.

Career Highlights

Francis has established a prominent career within pharmaceutical companies, most notably at Acura Pharmaceuticals, Inc., where he has implemented his innovative patent processes. His work has not only contributed to the growth of the company but also to advancements in the pharmaceutical industry.

Collaborations

Throughout his career, Charles Auxilium Francis has collaborated with esteemed individuals, including Zhaiwei Lin and Christopher Arne Kaldahl. These partnerships have fostered an environment of creativity and innovation, leading to the successful development of his patented processes.

Conclusion

The contributions of Charles Auxilium Francis to the field of opioid manufacturing are noteworthy, highlighted by his innovative patents and collaborations. His work continues to play a pivotal role in enhancing the efficacy and purity of opioid products, positioning him as a significant figure in pharmaceutical innovation.

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