Acura Pharmaceuticals, Inc.

Other

Halsey Drug Company, Inc.

Charles Auxilium Francis

Vijai Kumar

Kazimierz Grzegorz Antczak

Zhaiwei Lin

Christopher Arne Kaldahl

Oxycodone is manufactured in high yields and with a high purity using a composition including a thebaine component into 14-hydroxycodeinone and then reduction of 14-hydroxycodeinone to oxycodone.

Process for manufacturing opioid analgesics

A morphine component, e.g., a concentrate of poppy straw, is converted into codeine in high yield and high purity and in a highly controlled manner. The conversion process involves the following steps: (a) providing a solution or suspension of a morphine component in an inert solvent or a mixture of solvents; (b) methylating the resultant solution or suspension with a methylating agent in the presence of an alkaline ingredient; and (c) recovering the resultant codeine as the free base or as a salt.

Process for the production of opiates

Oxycodone is manufactured in high yields and with a high purity using codeine or a salt of codeine as the starting material. The manufacturing process involves the following steps:

Process for manufacturing oxycodone

Process for manufacturing thebaine

This handrail polishing flap is designed to depend from boat handrails when the boat is not in use, so as to clean and polish the handrails by wind power only. Primarily, it consists of a panel with a bristled plastic strip in the longitudinal middle portion that contains a cleaning and polishing agent that engages with the handrail. Mating hook and loop pile fasteners are secured to the flap for holding it together on the handrail, and pockets are provided in the end portion that depends downward from the handrail, for returning the flap to its full downward position after each movement back and forth caused by the wind.

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Valparaiso, IN, United States of America

Charles Auxilium Francis