Company Filing History:
3 out of 459 
3 out of 14 
1 out of 14 
Years Active: 1988-1997
Title: Charles A. Dinarello: Pioneer in Interleukin Research
Introduction
Charles A. Dinarello is a notable inventor based in Suffolk County, Massachusetts, recognized for his substantial contributions to the field of immunology. With three patents to his name, he has made significant strides in the understanding and application of interleukin-1 (IL-1) in therapeutic contexts, notably in immune response modulation.
Latest Patents
Among his latest patents, Dinarello has developed antibodies to IL-1.beta., which pertain to a nucleic acid that encodes human interleukin-1 and its fragments. This invention focuses on the cloning of complementary DNA (cDNA) synthesized from poly(A)RNA harvested from human monocytes stimulated by bacterial endotoxin. Furthermore, his invention includes antibodies that can specifically react to human IL-1.beta. proteins, pivotal in stimulating IL-2 production by activated T-cells and affecting B-cells and NK-cells.
Another significant patent by Dinarello addresses the IL-1.beta. protein precursor, encompassing similar nucleic acid sequences and methodologies as his other works. This overlap underscores his innovative approach in utilizing human IL-1 for therapeutic advancements aimed at enhancing immune responses.
Career Highlights
Throughout his career, Dinarello has collaborated with esteemed institutions such as Tufts College and Wellesley College, where he has significantly contributed to research advancements. His relentless pursuit of knowledge and innovation has solidified his reputation as a leader in his field.
Collaborations
Dinarello has worked alongside prominent figures in the research community, including Philip E. Auron and Andrew C. Webb. These collaborations have furthered his research endeavors and amplified the impact of his inventions in the scientific community.
Conclusion
Charles A. Dinarello's work, particularly in the realm of interleukin research, marks essential progress in understanding immune responses. His patented innovations provide valuable insights that can lead to effective therapies for various diseases, proving the significant role that inventors play in advancing science and medicine.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.