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Years Active: 2012-2025
Title: Chao Bai Huang: Innovator in Antibody Drug Conjugates
Introduction
Chao Bai Huang is a prominent inventor based in San Leandro, CA (US). He has made significant contributions to the field of biotechnology, particularly in the development of antibody drug conjugates. With a total of 6 patents to his name, Huang's work has the potential to impact therapeutic strategies in various medical applications.
Latest Patents
Huang's latest patents include innovative approaches to targeted therapy using CUB domain-containing protein 1 (CDCP1). The first patent provides materials and methods for CDCP1-targeted therapy, which aims to enhance the efficacy of treatments by specifically targeting this protein. His second patent focuses on antibody conjugates that incorporate a sulfatase motif-containing tag in the constant region of an immunoglobulin (Ig) heavy chain polypeptide. This technology allows for the conversion of the sulfatase motif by a formylglycine-generating enzyme (FGE), resulting in a formylglycine (fGly)-modified Ig heavy chain polypeptide. This modification enables the antibody to be covalently and site-specifically bound to a moiety of interest, creating a versatile antibody conjugate. The patent also details methods for producing these tagged Ig heavy chain polypeptides and their applications.
Career Highlights
Throughout his career, Chao Bai Huang has worked with notable companies such as R.P. Scherer Technologies, Inc. and Schering Corporation. His experience in these organizations has contributed to his expertise in the field of antibody development and drug conjugation.
Collaborations
Huang has collaborated with esteemed colleagues, including Yun Cheol Kim and David Rabuka. These partnerships have likely fostered innovative ideas and advancements in their shared field of research.
Conclusion
Chao Bai Huang is a distinguished inventor whose work in antibody drug conjugates and targeted therapies showcases his commitment to advancing medical science. His contributions are paving the way for new therapeutic options that could significantly improve patient outcomes.