The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 10, 2012
Filed:
Oct. 20, 2008
Sumant Ramachandra, Northbrook, IL (US);
Walter Robert Bishop, Pompton Plains, NJ (US);
Linda Masat, Walnut Creek, CA (US);
Chao Bai Huang, San Leandro, CA (US);
Toshihiko Takeuchi, Oakland, CA (US);
Seema Kantak, Pacifica, CA (US);
Chin-yi Huang, Fremont, CA (US);
Sumant Ramachandra, Northbrook, IL (US);
Walter Robert Bishop, Pompton Plains, NJ (US);
Linda Masat, Walnut Creek, CA (US);
Chao Bai Huang, San Leandro, CA (US);
Toshihiko Takeuchi, Oakland, CA (US);
Seema Kantak, Pacifica, CA (US);
Chin-Yi Huang, Fremont, CA (US);
Schering Corporation, Kenilworth, NJ (US);
Abstract
Disclosed herein are fully human antibodies and antigen-binding fragments thereof that specifically bind human VEGF and inhibit VEGF binding to VEGF-R1 and VEGF-R2, and therefore inhibit VEGF signaling. The antibodies and antigen-binding fragments disclosed herein may be used, for example, to treat angiogenesis and conditions associated with angiogenesis both in vivo and in vitro.