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Title: Chanoch Kronman: Innovator in Biological Research
Introduction
Chanoch Kronman is a notable inventor based in Rehovot, Israel, recognized for his contributions to biological research. With a total of three patents to his name, Kronman has made significant advancements in the detection of toxins and treatment methods for organophosphate poisoning.
Latest Patents
Kronman's latest patents include innovative methods for detecting exposure to RIP II toxins. This invention focuses on identifying the enzymatic activity of the toxin on 28sRNA, utilizing sensitive and specific amplification steps that enable detection in clinical samples. Another significant patent involves a uniformly conjugated serine hydrolase, which serves as an organophosphate scavenger. This invention boasts an extended residence time in mammalian circulation, making it useful for both preventive and therapeutic treatment of organophosphate poisoning. The scavenger is a uniformly pegylated serine hydrolase, where specific lysine residues are replaced through site-directed mutagenesis to ensure effective PEG coupling.
Career Highlights
Throughout his career, Chanoch Kronman has worked with esteemed organizations, including the State of Israel Prime Minister's Office and the Israel Institute for Biological Research. His work has contributed to advancements in biological safety and therapeutic interventions.
Collaborations
Kronman has collaborated with notable colleagues such as Ofer Cohen and Baruch Velan, enhancing the impact of his research through teamwork and shared expertise.
Conclusion
Chanoch Kronman's innovative work in biological research and his patented inventions highlight his significant contributions to the field. His dedication to advancing detection methods and treatment options continues to influence the scientific community.