Changming Dong

Title: Changming Dong: Innovator in Pharmaceutical Synthesis

Introduction

Changming Dong is a notable inventor based in Guizhou, China. He has made significant contributions to the field of pharmaceutical synthesis, particularly through his innovative methods for creating chemical compounds that serve as intermediates in drug development.

Latest Patents

One of his key patents is titled "Method for synthesizing 1,7-naphthyridine derivatives." This invention discloses a method that relates to the technical field of synthesizing pharmaceutical intermediates and organic chemical intermediates. The method involves several steps: first, using 2-chloro-3-amino-pyridine as Compound I as a starting material, and protecting an amino group to prepare Compound II. Next, Compound II reacts with an aldehydation reagent under alkaline conditions to obtain Compound III. Finally, Compound III is cyclized with acrylate compounds under the action of Lewis acid to prepare Compound IV. This innovative approach has the potential to enhance the efficiency of synthesizing important pharmaceutical compounds.

Career Highlights

Changming Dong is currently associated with Chengda Pharmaceuticals Co., Ltd., where he continues to work on advancing pharmaceutical synthesis techniques. His expertise in this area has positioned him as a valuable asset to the company and the broader scientific community.

Collaborations

He collaborates with talented coworkers, including Wei Qian and Yuhua Shi, who contribute to his research and development efforts. Their combined expertise fosters a productive environment for innovation and discovery.

Conclusion

Changming Dong's contributions to the field of pharmaceutical synthesis, particularly through his patent on 1,7-naphthyridine derivatives, highlight his role as an influential inventor. His work not only advances scientific knowledge but also has practical implications for the development of new pharmaceuticals.