The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2025
Filed:
Nov. 17, 2020
Chengda Pharmaceuticals Co., Ltd., Zhejiang, CN;
Wei Qian, Zhejiang, CN;
Yuhua Shi, Shanghai, CN;
Xing Huang, Zhejiang, CN;
Changming Dong, Guizhou, CN;
Junkui Dang, Gansu, CN;
Zhipeng Wang, Hainan, CN;
Yu Feng, Sichuan, CN;
Hong Xu, Zhejiang, CN;
Zongxi Huang, Anhui, CN;
Ye Chen, Zhejiang, CN;
Huafei Shen, Zhejiang, CN;
Jun Zhang, Anhui, CN;
ChengDa Pharmaceuticals Co., Ltd., Zhejiang, CN;
Abstract
The invention discloses a method for synthesizing 1,7-naphthyridine derivatives, which relates to the technical field of synthesizing pharmaceutical intermediates and organic chemical intermediates, wherein the method includes: (1) 2-chloro-3-amino-pyridine being used as Compound I as a starting material, and protecting an amino group to prepare Compound II; (2) the Compound II reacting with an aldehydation reagent under alkaline conditions to obtain Compound III; (3) cyclizing the Compound III with acrylate compounds under the action of Lewis acid to prepare compound IV.