Changhua Ke

Title: Innovations of Changhua Ke in Medicinal Chemistry

Introduction

Changhua Ke is a notable inventor based in Xi'an, China. He has made significant contributions to the field of medicinal chemistry, particularly through his innovative work on pleuromutilin derivatives. His research focuses on developing compounds that can effectively combat pathogenic microorganisms.

Latest Patents

Changhua Ke holds a patent for a pleuromutilin derivative containing a thiazole-pyridine benzyl quaternary ammonium salt side chain. This invention includes a preparation method and its applications, showcasing the potential of this compound in medicinal use. The synthesis method he developed is characterized by easily available raw materials, simple operation, and high product yield, making it suitable for industrial production. In vitro pharmacological experiments have demonstrated that this pleuromutilin derivative exhibits good antibacterial and anti-mycoplasma activities, along with excellent solubility. These findings indicate that his invention holds great promise for the development of new anti-pathogenic microorganism drugs.

Career Highlights

Changhua Ke is affiliated with the Shaanxi University of Science and Technology, where he continues to advance his research in medicinal chemistry. His work has not only contributed to academic knowledge but also has practical implications in the pharmaceutical industry.

Collaborations

Changhua has collaborated with notable colleagues, including Chenguan Liang and Kairui Kang, to further enhance the impact of his research in the field.

Conclusion

Changhua Ke's innovative work in developing pleuromutilin derivatives represents a significant advancement in medicinal chemistry. His contributions are poised to make a lasting impact on the development of effective treatments for infectious diseases.