Changhua Ji

Title: Innovations of Changhua Ji in Antiviral Research

Introduction

Changhua Ji is a notable inventor based in Shanghai, China. He has made significant contributions to the field of antiviral research, particularly in the development of methods for screening substances that inhibit hepadnaviruses, such as the hepatitis B virus. With a total of two patents to his name, Ji's work is recognized for its potential impact on public health.

Latest Patents

Changhua Ji's latest patents focus on the "Tagged hepadnavirus E antigen and its use in screening antiviral substances." This invention relates to methods and uses for screening anti-hepadnaviral substances, specifically targeting the capacity to inhibit covalently closed circular (ccc) DNA of hepadnaviruses. The methods utilize cells that contain a nucleic sequence encoding a tagged hepadnavirus E antigen, such as the Hepatitis B virus E antigen (HBeAg). Additionally, the invention provides nucleic acid sequences encoding the tagged hepadnavirus E antigen and the proteins encoded by these sequences. Kits for use in the screening methods are also included in this patent.

Career Highlights

Throughout his career, Changhua Ji has worked with esteemed institutions, including Drexel University and the Baruch S. Blumberg Institute. His experience in these organizations has allowed him to collaborate with other experts in the field and contribute to groundbreaking research in antiviral therapies.

Collaborations

Some of Changhua Ji's notable coworkers include Haitao Guo and Dawei Cai. Their collaborative efforts have further advanced the research and development of antiviral substances.

Conclusion

Changhua Ji's innovative work in the field of antiviral research highlights his commitment to improving health outcomes through scientific advancements. His patents and collaborations reflect a dedication to combating viral infections, particularly hepatitis B.