Chang Su Lim

Title: Chang Su Lim: Innovator in Two-Photon Probes

Introduction

Chang Su Lim is a prominent inventor based in Seoul, South Korea. He has made significant contributions to the field of imaging technology, particularly through his innovative two-photon probes. With a total of 2 patents, his work focuses on the detection and quantitative estimation of metal ions in biological tissues.

Latest Patents

Chang Su Lim's latest patents include a two-photon probe designed for detecting copper(II) ions. This probe allows for in-vivo imaging with high selectivity for copper(II) ions. It can detect intracellular free copper(II) ions for extended periods, achieving a penetration depth greater than 90 µm in living cells and tissues. The method quantitatively estimates copper(II) ion concentration in vivo by analyzing the ratio of blue emission intensity at 400-450 nm to red emission intensity at 550-650 nm. Another notable patent involves a two-photon fluorescent dye for imaging total sulfide in vivo. This dye can detect hydrosulfide ions and allows for the quantitative estimation of total sulfide concentration in biological systems.

Career Highlights

Throughout his career, Chang Su Lim has worked with notable organizations, including the Korea University Research and Business Foundation and SFC Co., Ltd. His expertise in developing advanced imaging techniques has positioned him as a leader in his field.

Collaborations

Chang Su Lim has collaborated with esteemed colleagues such as Bong-Rae Cho and Eun Sun Kim. These partnerships have further enhanced his research and development efforts in the area of two-photon imaging.

Conclusion

Chang Su Lim's innovative work in the development of two-photon probes has significant implications for biomedical research and diagnostics. His contributions continue to advance the understanding of metal ion dynamics in living organisms.