Company Filing History:
Years Active: 2015
Title: Biography of Chandrashekar Trimbak Gaikwad
Introduction
Chandrashekar Trimbak Gaikwad is an accomplished inventor based in Maharashtra, India. He is known for his significant contributions to the field of pharmaceuticals, particularly in the development of novel compounds.
Latest Patents
Gaikwad holds a patent for a process for the preparation of bosentan, which is a novel ammonium salt of Bosentan. This patent discloses a unique method that may yield either crystalline or amorphous forms of the salt. The innovative single pot process involves reacting 4,6-dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine with 4-tert-butylbenzenesulfonamide in the presence of a solvent and a base. The process further includes the addition of ethylene glycol to the reaction mass, leading to the isolation of the ammonium salt of Bosentan. This compound is then converted into Bosentan and subsequently into Bosentan Monohydrate, which is substantially free from dimer and 6-hydroxy impurities.
Career Highlights
Chandrashekar Trimbak Gaikwad is currently associated with Megafine Pharma Pvt. Ltd., where he continues to innovate in the pharmaceutical sector. His work has been instrumental in advancing the preparation methods of important pharmaceutical compounds.
Collaborations