Company Filing History:
Years Active: 1982-1987
Title: Innovations of Chander P Bahl
Introduction
Chander P Bahl is a notable inventor based in El Cerrito, CA. He holds a total of 3 patents that contribute significantly to the field of biotechnology. His work primarily focuses on advancements in genetic engineering and insulin production.
Latest Patents
One of his latest patents involves a plasmid for producing human insulin. This innovation describes recombinant plasmids that carry the structural gene for human proinsulin in an expressible form. The human proinsulin structural gene is fused to a functional transport sequence, allowing host organisms transformed by the recombinant plasmids to express preproinsulin in vivo. This preproinsulin is then transported across the host organism's cell wall. Following its recovery, in vitro methods are employed to convert the human proinsulin into human insulin.
Another significant patent by Bahl outlines a method for using an amino-terminus DNA sequence to synthesize specific double-stranded DNA. This method utilizes messenger RNA templates to construct DNA strands complementary to the templates. The process involves forming DNA strands using a non-specific 3' hydroxy terminus primer and blocking the free 3' hydroxy to prevent self-priming. Primer segments complementary to a portion of the amino terminus-coding end of the desired single strands are then provided and extended with a suitable polymerase to complete the complementary strands.
Career Highlights
Chander P Bahl has made substantial contributions to the field of biotechnology through his innovative patents. He is currently associated with Cetus Corporation, where he continues to work on groundbreaking research and development projects.
Collaborations
Bahl collaborates with various professionals in his field, including his coworker Jack H Nunberg, to further enhance the impact of his inventions.
Conclusion
Chander P Bahl's contributions to biotechnology, particularly in insulin production and DNA synthesis, showcase his innovative spirit and dedication to advancing scientific knowledge. His work continues to influence the field and pave the way for future advancements.