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For the Inventor, By the Inventor

Newton, MA, United States of America

Chafen Lu

USPTO Granted Patents = 10 

Average Co-Inventor Count = 3.2

ph-index = 3

Forward Citations = 24(Granted Patents)


Location History:

  • Newton, MA (US) (2007 - 2021)
  • Chestnut Hill, MA (US) (2017 - 2021)

Company Filing History:

goldMedal6 out of 32 
 
Center for Blood Research, Inc.
 patents
silverMedal4 out of 1,036 
 
Children's Medical Center Corporation
 patents

Years Active: 2007-2021

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10 patents (USPTO):Explore Patents
1. 11136383 - Methods and compositions for modulaton of transforming growth factor beta-regulated functions (2021-10-05),
2. 11104713 - Modified integrin polypeptides, modified integrin polypeptide dimers, and uses thereof (2021-08-31),
3. 10273283 - Modified integrin polypeptides, modified integrin polypeptide dimers, and uses thereof (2019-04-30),
4. 9580482 - Conformation-stabilized TRAP antigens (2017-02-28),
5. 8241627 - Modified polypeptides stabilized in a desired conformation and methods for producing same (2012-08-14),
6. 7968284 - Modified polypeptides stabilized in a desired conformation and methods for producing same (2011-06-28),
7. 7879577 - Modified polypeptides stabilized in a desired conformation and methods for producing same (2011-02-01),
8. 7674604 - Modified polypeptides stabilized in a desired conformation and methods for producing same (2010-03-09),
9. 7241869 - Modified polypeptides stabilized in a desired conformation and methods for producing same (2007-07-10),
10. 7160541 - Modified polypeptides stabilized in a desired conformation and methods for producing same (2007-01-09),

Title: The Innovative Contributions of Chafen Lu

Introduction

Chafen Lu is a prominent inventor based in Newton, MA, known for his significant contributions to the field of biomedical research. With a total of 10 patents to his name, Lu has made remarkable advancements in understanding and modulating biological processes.

Latest Patents

Among his latest patents, Lu has developed methods and compositions for the modulation of transforming growth factor beta-regulated functions. This patent discloses compositions and methods for modulating the activity of TGF-β, particularly focusing on the release of active TGF-β from an LRRC33-TGF-β prodomain-TGF-β ternary complex. Another notable patent involves modified integrin polypeptides and their dimers, which are described as having applications in characterizing integrin-ligand interactions and identifying integrin ligands. These innovations have the potential to serve as inhibitors of integrins, showcasing Lu's commitment to advancing medical science.

Career Highlights

Chafen Lu has worked with esteemed organizations such as the Center for Blood Research and the Children's Medical Center Corporation. His work in these institutions has allowed him to collaborate with leading experts in the field, further enhancing his research and innovation capabilities.

Collaborations

Lu has collaborated with notable individuals, including Timothy Alan Springer and Motomu Shimaoka. These partnerships have contributed to the depth and impact of his research.

Conclusion

Chafen Lu's innovative work and numerous patents reflect his dedication to advancing biomedical research. His contributions continue to influence the field and pave the way for future discoveries.

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