Location History:
- Columbia, SC (US) (2021)
- Irmo, SC (US) (2023)
Company Filing History:
Years Active: 2021-2023
Title: Chad Beneker: Innovator in Cancer Treatment and Kinase Inhibition
Introduction
Chad Beneker is a prominent inventor based in Columbia, SC (US), known for his significant contributions to the field of biochemistry and cancer treatment. With a total of 2 patents, he has developed innovative compounds that target critical pathways in disease progression.
Latest Patents
Beneker's latest patents include groundbreaking work on inhibitors of lysyl oxidases. These novel compounds effectively block the activity of LOX family members, demonstrating good IC50 values and minimal cellular toxicity below 10 µM. They also induce sensitization of cells to doxorubicin and exhibit strong activity in recombinant LOX/LOXL2 assays. Additionally, the compounds possess a drug-like chemical structure without a PAINS flag, making them promising candidates for treating cancer, organ fibrosis, neurodegenerative, and cardiovascular diseases.
Another significant patent involves peptide-based inhibitors of Raf kinase protein dimerization and kinase activity. This invention describes compositions that modify Raf kinase protein dimerization, focusing on peptides with a high binding affinity for the dimer interface of Raf kinase proteins. The methods outlined aim to inhibit tumor growth, showcasing the potential of these peptides in cancer therapy.
Career Highlights
Chad Beneker is affiliated with the University of South Carolina, where he conducts research and develops his innovative solutions. His work has garnered attention for its potential impact on cancer treatment and related fields.
Collaborations
Beneker collaborates with esteemed colleagues, including Campbell McInnes and Ozgur Sahin, to further advance his research and innovations.
Conclusion
Chad Beneker's contributions to the field of biochemistry and cancer treatment through his patents highlight his role as a leading inventor. His innovative approaches to inhibiting critical proteins in disease pathways pave the way for future advancements in medical treatments.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.