Company Filing History:
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Years Active: 2003-2009
Title: Celine Viglietta: Innovator in Transgenic Research
Introduction
Celine Viglietta is a prominent inventor based in Versailles, France. She has made significant contributions to the field of transgenic research, particularly in the area of gene expression in animals. With a total of two patents to her name, her work has implications for both agriculture and medicine.
Latest Patents
Celine Viglietta's latest patents include groundbreaking inventions. One patent focuses on the position-independent and tissue-specific expression of a transgene in the milk of transgenic animals. This invention relates to an isolated insulator DNA molecule that consists of the 5' and 3' regions of the porcine wrap gene locus. It provides a method for insulating the expression of an introduced heterologous gene from silencing and variegation effects in chromatin. The invention also encompasses mammalian cells that include this insulator DNA molecule and non-human animals capable of expressing a polypeptide of interest in milk. Another notable patent is for a transgenic rabbit that expresses a functional human lipoprotein (a). This rabbit contains genomic DNA sequences that encode apolipoprotein (a) and apolipoprotein B polypeptides, which can combine to produce lipoprotein (a). This invention is significant for identifying compounds effective in treating human diseases associated with Lp(a) expression.
Career Highlights
Throughout her career, Celine Viglietta has worked with notable organizations. She has been associated with Aventis Pharmaceuticals Inc. and the Institut National De La Recherche Agronomique. Her work in these institutions has allowed her to advance her research and contribute to the scientific community.
Collaborations
Celine has collaborated with esteemed colleagues in her field, including Louis-Marie Houdebine and Didier Rouy. These collaborations have further enriched her research and innovation efforts.
Conclusion
Celine Viglietta is a trailblazer in transgenic research, with her patents paving the way for advancements in gene expression and potential medical treatments. Her contributions continue to impact the fields of agriculture and medicine significantly.