The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2003
Filed:
Jan. 08, 1999
Applicant:
Inventors:
Didier Rouy, Thiais, FR;
Nicolas Duverger, Paris, FR;
Florence Emmanuel, Aubervilliers, FR;
Patrice Denefle, Saint Maur, FR;
Louis-Marie Houdebine, Buc, FR;
Celine Viglietta, Versailles, FR;
Edward M. Rubin, Berkeley, CA (US);
Steven D. Hughes, Oakland, CA (US);
Assignee:
Aventis Pharmaceuticals, Inc., Bridgewater, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 3/300 ; A01K 6/700 ; A01K 6/7027 ; C12N 1/500 ;
U.S. Cl.
CPC ...
G01N 3/300 ; A01K 6/700 ; A01K 6/7027 ; C12N 1/500 ;
Abstract
A transgenic rabbit which has in its genomic DNA sequences that encode apolipoprotein (a) and apolipoprotein B polypeptides which are capable of combining to produce lipoprotein (a), a process for creating such a rabbit, and the use of the rabbit to identify compounds which are effective in the treatment of human diseases which are associated with, induced and/or exacerbated by Lp(a) expression.