The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2009
Filed:
Dec. 21, 2001
Sylvie Rival, Morsang-sur-Orge, FR;
Celine Viglietta, Versailles, FR;
Joe Attal, Sarcelles, FR;
Louis-marie Houdebine, Buc, FR;
Sylvie Rival, Morsang-sur-Orge, FR;
Celine Viglietta, Versailles, FR;
Joe Attal, Sarcelles, FR;
Louis-Marie Houdebine, Buc, FR;
Institut National de la Recherche Agronomique, Paris, FR;
Abstract
The present invention relates to an isolated insulator DNA molecule consisting of the 5' and 3′ regions of the porcine wrap gene locus and a method for insulating the expression of an introduced heterologous gene from silencing and variegation effect in chromatin into which the gene has integrated. The invention is also directed to mammalian cells comprising said insulator DNA molecule and non human animals obtained therefrom, which are preferably able to express a polypeptide of interest in milk.