Cedric Orelle

Title: Cedric Orelle: Innovator in Engineered Ribosomes

Introduction

Cedric Orelle is a notable inventor based in Chicago, IL (US). He has made significant contributions to the field of biotechnology, particularly in the development of engineered ribosomes. His work focuses on enhancing the capabilities of ribosomes to support the translation of sequence-defined polymers.

Latest Patents

Cedric Orelle holds a patent for "Ribosomes with tethered subunits." This innovative patent discloses an engineered ribosome that includes a tethered subunit arrangement. The engineered ribosome supports the translation of a sequence-defined polymer. The patent also outlines methods for making and using the engineered ribosome, including a method for preparing a sequence-defined polymer using the engineered ribosome in a two-protein translation system. Furthermore, the engineered ribosomes can be utilized in methods for incorporating unnatural amino acids into a sequence-defined polymer. The patent also includes optimized polynucleotide sequences for use as tethers and Shine-Dalgarno/anti-Shine-Dalgarno sequences.

Career Highlights

Throughout his career, Cedric Orelle has worked with prestigious institutions such as Northwestern University and the University of Illinois. His research has contributed to advancements in the understanding and application of ribosomal engineering.

Collaborations

Cedric has collaborated with notable colleagues, including Michael Christopher Jewett and Do Soon Kim. These collaborations have further enriched his research and innovation in the field.

Conclusion

Cedric Orelle's work in engineered ribosomes represents a significant advancement in biotechnology. His innovative approaches and collaborations continue to influence the field, paving the way for future discoveries and applications.