Caroline Horn

Title: **Caroline Horn: Innovator in Nucleic Acid Technologies**

Introduction

Caroline Horn, based in Los Altos, California, is a prominent inventor recognized for her innovative contributions to the field of nucleic acid technologies. With two patents to her name, her work significantly advances pest control methods and nucleic acid analysis.

Latest Patents

Horn's latest patents include:

1. **Insecticidal CRY1B Variants Having Improved Activity Spectrum and Uses Thereof** - This invention focuses on nucleic acids and their variants derived from specific strains that encode polypeptides with enhanced pesticidal activity against various insect pests, including Lepidoptera and Coleopteran. The disclosure offers isolated nucleic acids encoding these pesticidal proteins, formulations, DNA constructs, and transformed microorganisms and plants, all of which are designed to control plant pests effectively.

2. **Nucleic Acid Quantification Using Concentration-Specific Barcodes** - This patent presents a reagent system aimed at nucleic acid analysis. It involves multiple sets of oligonucleotides, each containing a competitor oligonucleotide that binds to the target sequence and varies in concentration. Additionally, a detector oligonucleotide, which also binds to the target sequence, carries a barcode indicating the competitor's concentration, facilitating the analysis of nucleic acid samples.

Career Highlights

Throughout her career, Caroline Horn has made significant strides in her field. She has worked at Pioneer Hi-Bred International, Inc. and Leland Stanford Junior University, where she applied her expertise to groundbreaking research and development in biological sciences.

Collaborations

Horn has collaborated with notable professionals, including Sabina Lau and Michi Izumi Willcoxon. These collaborations have helped her expand her research and contribute to advanced technologies in her area of expertise.

Conclusion

Caroline Horn stands out as an influential inventor in the realm of nucleic acid technologies. Her patents reflect her dedication to developing innovative solutions for pest control and molecular analysis. Through her work and collaborations, Horn exemplifies the spirit of innovation in scientific research.