Location History:
- Washington, DC (US) (1980 - 1990)
- Bethesda, MD (US) (1991 - 2023)
Company Filing History:
24 out of 8,684 
4 out of 115 
2 out of 28 
Years Active: 1980-2023
Title: Carl R Alving: Innovator in Vaccine Delivery and Adjuvant Formulations
Introduction:
Carl R Alving, a renowned inventor based in Bethesda, MD, has made significant contributions to the field of pharmaceutical compositions and vaccine delivery. With 34 patents to his name, he has demonstrated expertise in developing adjuvant formulations that enhance the effectiveness and safety of vaccines. This article explores his latest patents, career highlights, collaborations, and the impact of his work in the field.
Latest Patents:
Carl R Alving has recently been involved in groundbreaking inventions related to recombinant circumsporozoite protein compositions and methods for vaccine delivery. One of his latest patents involves a pharmaceutical composition comprising antigens and an adjuvant composition containing a saponin and a liposome. The liposome in the composition includes monophosphoryl lipid A (MPLA), cholesterol, and a phospholipid in a liquid crystalline state at or above 23°C. The patented invention aims to improve the efficacy of vaccines through optimized adjuvant composition.
Another patent by Alving focuses on a non-toxic adjuvant formulation comprising a monophosphoryl lipid A (MPLA)-containing liposome composition and a saponin. The adjuvant formulation incorporates a lipid bilayer containing phospholipids with hydrocarbon chains possessing a melting temperature in water of 23°C or higher. A cholesterol concentration ranging from 55% to 71% (mol/mol) enhances the effectiveness of the formulation while maintaining minimal toxicity.
Career Highlights:
Throughout his career, Carl R Alving has amassed an impressive collection of patents and achievements. His expertise lies in developing innovative solutions for vaccine delivery and adjuvant formulations. Working for esteemed organizations like The United States of America as Represented by the Secretary of and The Liposome Company, Inc., he has made a lasting impact on the field through his research and inventions.
Collaborations:
Collaboration often paves the way for novel breakthroughs in the field of innovations. Carl R Alving has worked with noteworthy colleagues, including Gregory M Glenn and Gary R Matyas. These collaborations have fostered a multidisciplinary approach, combining expertise in microbiology, immunology, and pharmaceutical sciences. The joint efforts of Alving and his coworkers have led to remarkable advancements in vaccine delivery and adjuvant formulations.
Conclusion:
Carl R Alving's relentless pursuit of innovation in vaccine delivery and adjuvant formulations has yielded significant contributions to the field. Through his numerous patents, including the recent inventions in recombinant circumsporozoite protein compositions and adjuvant formulations, Alving has demonstrated his commitment to enhancing the efficacy and safety of vaccines. Collaborations with esteemed colleagues have further amplified the impact of his work. As the world continues to face challenges in immunization, the contributions of inventors like Carl R Alving pave the way for future advancements in public health and medicine.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.