Caitlin L Goshert

Title: Innovations of Caitlin L Goshert

Introduction

Caitlin L Goshert is an accomplished inventor based in Boston, MA. She has made significant contributions to the field of biotechnology, particularly in the area of DNA assembly. With a total of two patents to her name, Goshert's work is paving the way for advancements in genetic engineering.

Latest Patents

Goshert's latest patents focus on nuclease-mediated DNA assembly. The methods provided in her patents involve assembling at least two nucleic acids using a sequence-specific nuclease agent, such as a gRNA-Cas complex. This innovative approach allows for the creation of end sequences that have complementarity, enabling the assembly of overlapping complementary sequences. The nuclease agent can create double-strand breaks in dsDNA to generate overlapping end sequences or can create nicks on each strand to produce complementary overhanging end sequences. This method can assemble any nucleic acids with overlapping sequences or utilize a joiner oligo to assemble sequences without complementary ends.

Career Highlights

Caitlin L Goshert is currently employed at Regeneron Pharmaceuticals, Inc., where she continues to develop her innovative ideas. Her work is instrumental in advancing the capabilities of genetic engineering and biotechnology.

Collaborations

Some of her notable coworkers include Chris Schoenherr and John R McWhirter, who contribute to the collaborative environment that fosters innovation at Regeneron Pharmaceuticals.

Conclusion

Caitlin L Goshert's contributions to the field of biotechnology through her patents and work at Regeneron Pharmaceuticals highlight her role as a leading inventor in DNA assembly methods. Her innovative approaches are set to make a lasting impact on genetic engineering.