Location History:
- West University, TX (US) (1996)
- Houston, TX (US) (1999 - 2006)
- Lansdale, PA (US) (2006)
Company Filing History:
6 out of 600 
5 out of 4,770 
2 out of 38 
Years Active: 1996-2006
Title: C Thomas Caskey: Innovator in Genetic Research
Introduction
C Thomas Caskey is a prominent inventor based in Houston, TX (US), known for his significant contributions to genetic research. He holds a total of 11 patents, showcasing his innovative work in the field of molecular genetics.
Latest Patents
Among his latest patents is the development of a novel human and mouse DNA sequence that encodes the gene CG1CE, which, when mutated, is responsible for Best's macular dystrophy. This patent provides genomic CG1CE DNA as well as cDNA that encodes the CG1CE protein. Additionally, it includes methods for expressing the CG1CE protein in recombinant systems and diagnostic methods to detect patients with mutant CG1CE genes. Another notable patent is the parallel primer extension approach to nucleic acid sequence analysis. This method involves analyzing a polynucleotide of interest by using consecutive oligonucleotide primers that differ by one base at the growing end. The process includes annealing the polynucleotide to the primers, subjecting them to single base extension reactions, and observing the location and identity of each terminating nucleotide to analyze the nucleotide sequence.
Career Highlights
Caskey has had a distinguished career, working with esteemed organizations such as Baylor College of Medicine and Merck & Company, Inc. His work has significantly advanced the understanding of genetic disorders and the development of diagnostic methods.
Collaborations
Throughout his career, Caskey has collaborated with notable colleagues, including John Shumaker and Andres Metspalu. These collaborations have further enriched his research and contributions to the field.
Conclusion
C Thomas Caskey's innovative work in genetic research has led to important advancements in understanding and diagnosing genetic disorders. His contributions continue to impact the field significantly.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.