The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2006
Filed:
Feb. 22, 1999
Konstantin Petrukhin, Collegeville, PA (US);
C. Thomas Caskey, Lansdale, PA (US);
Michael Metzker, Fort Washington, PA (US);
Claes Wadelius, Upsala, SE;
Konstantin Petrukhin, Collegeville, PA (US);
C. Thomas Caskey, Lansdale, PA (US);
Michael Metzker, Fort Washington, PA (US);
Claes Wadelius, Upsala, SE;
Merck & Co., Inc., Rahway, NJ (US);
Abstract
Novel human and mouse DNA sequences that encode the gene CG1CE, which, when mutated, is responsible for Best's macular dystrophy, are provided. Provided are genomic CG1CE DNA as well as cDNA that encodes the CG1CE protein. Also provided is CG1CE protein encoded by the novel DNA sequences. Methods of expressing CG1CE protein in recombinant systems are provided. Also provided are diagnostic methods that detect patients having mutant CG1CE genes.