C Nagaraja Sridhar

Title: C Nagaraja Sridhar: Innovator in Nucleic Acid Detection

Introduction

C Nagaraja Sridhar is a prominent inventor based in Simi Valley, CA (US). He has made significant contributions to the field of nucleic acid detection, holding a total of 12 patents. His work focuses on developing innovative methods and compositions that enhance the efficiency and accuracy of nucleic acid processing.

Latest Patents

One of his latest patents is titled "Sample processing to release nucleic acids for direct detection." This invention describes compositions and methods for releasing nucleic acids from cells in a form that is suitable for labeling, capture, amplification, or detection in a single reagent addition step. The compositions include a lipid, membrane fluidizing compound, enzyme for degrading cell structure, metal chelators, or one or more nucleic acid probes or primers complementary to the nucleic acid to be detected. The compositions are non-denaturing and non-inhibitory of enzymes or proteins that are used in nucleic acid release, amplification, labeling, or detection. The invention also provides kits for performing the above methods.

Another notable patent is "Method of labeling a nucleic acid amplicon with simultaneous contamination prevention." This invention relates to methods of amplifying nucleic acids to minimize contamination by products of earlier amplification reactions. More particularly, it involves using nucleic acid labels that inhibit further amplification of the amplicon, along with compositions that are useful to accomplish this task. The present invention focuses on photoreactive complexes of a binding ligand, a binding enhancer, and a label.

Career Highlights

Throughout his career, C Nagaraja Sridhar has worked with notable companies such as Gen-Probe, Inc. and Applied Gene Technologies, Inc. His experience in these organizations has contributed to his expertise in the field of nucleic acid technology.

Collaborations

C Nagaraja Sridhar has collaborated with talented individuals, including Nanibhushan Dattagupta and Aditya Ranjan Das. These collaborations have further enriched his work and innovations in nucleic acid detection.

Conclusion

C Nagaraja Sridhar is a distinguished inventor whose contributions to nucleic acid detection have paved the way for advancements in the field. His innovative patents and collaborations reflect his commitment to enhancing scientific research and applications.