Company Filing History:
Years Active: 1981-2005
Title: C Anthony Hunt: Innovator in Biochemical Assays
Introduction
C Anthony Hunt is a prominent inventor based in San Francisco, CA. He has made significant contributions to the field of biochemistry, particularly in the development of novel assay methods. With a total of 10 patents to his name, his work has had a substantial impact on the understanding of estrogenic activity and immune response modulation.
Latest Patents
One of Hunt's latest patents is titled "Methods for screening compounds for estrogenic activity." This invention provides novel assay methods for identifying compounds that may have both estrogen agonist and antagonist properties. The assay utilizes cells comprising promoters with an AP1 site linked to a reporter gene. Compounds capable of inducing or blocking the expression of the reporter gene can thus be identified. These compounds may be further tested for their ability to modulate the standard estrogen response.
Another significant patent is "Polynucleotide decoys that inhibit MHC-II expression and uses thereof." This invention introduces a newly discovered class of polynucleotide decoys that can competitively inhibit the binding of transcription factors to the X-box sequence, which is essential for the expression of MHC-II genes. The invention also outlines methods for preparing these decoys and their applications. Notably, these decoys can inhibit the expression of HLA molecules on donor cells or organs, rendering them invisible to the host's immune system. Additionally, they can be utilized in treating individuals with autoimmune diseases or infections such as hepatitis B virus and cytomegalovirus.
Career Highlights
C Anthony Hunt is affiliated with the University of California, where he continues to advance research in his field. His innovative work has garnered attention and respect within the scientific community.
Collaborations
Hunt has collaborated with notable colleagues, including Peter J Kushner and Paul Webb, contributing to various research projects and enhancing the impact of his inventions.
Conclusion
C Anthony Hunt's contributions to biochemistry through his patents and research have paved the way for advancements in understanding hormonal activity and immune responses. His work continues to influence the scientific community and offers potential solutions for various medical challenges.
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