The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 03, 1998

Filed:

Mar. 27, 1995
Applicant:
Inventors:

Peter Kushner, San Francisco, CA (US);

Paul Webb, San Francisco, CA (US);

Renee Williard, San Francisco, CA (US);

C Anthony Hunt, San Francisco, CA (US);

Gabriella Lopez, San Francisco, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ; C12Q / ; C12N / ;
U.S. Cl.
CPC ...
435-6 ; 435-71 ; 435-72 ; 435-721 ; 435-723 ; 435 691 ; 4351723 ; 435 29 ; 436501 ; 536 241 ;
Abstract

The present invention provides novel assay methods for identifying compounds that may have both estrogen agonist and antagonist properties. In particular, the assay use cells comprising promoters having an AP1 site linked to a reporter gene. Compounds capable of inducing or blocking expression of the reporter gene can thus be identified. The compounds may be further tested for the ability to modulate the standard estrogen response, as well.


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