Bryan Hoglund

Title: Innovations by Inventor Bryan Hoglund

Introduction

Bryan Hoglund is an accomplished inventor based in Pleasanton, CA (US). He has made significant contributions to the field of molecular biology and medical diagnostics. With a total of 2 patents, his work focuses on critical advancements in detecting genetic mutations and organ transplant rejection.

Latest Patents

Hoglund's latest patents include a groundbreaking invention related to the epidermal growth factor receptor (EGFR). This invention identifies a new in-frame deletion found in exon 19 of the EGFR gene, which is frequently mutated in tumors. The methods developed by Hoglund allow for the detection of this mutation, providing essential tools for prognosis and predicting treatment responses based on the mutation's presence or absence. Another notable patent involves a non-invasive method for early detection of solid organ transplant rejection. This method utilizes quantitative analysis of mixtures through deep sequencing of HLA gene amplicons, enabling the detection of donor-specific HLA alleles in a blood sample from transplant recipients.

Career Highlights

Throughout his career, Bryan Hoglund has worked with prominent organizations such as Roche Molecular Systems, Inc. and The Scripps Research Institute. His experience in these institutions has allowed him to refine his expertise and contribute to significant advancements in medical technology.

Collaborations

Hoglund has collaborated with esteemed colleagues, including Henry A. Erlich and Cherie Holcomb. These partnerships have fostered innovation and have been instrumental in the development of his patented technologies.

Conclusion

Bryan Hoglund's contributions to the field of molecular diagnostics are noteworthy. His innovative patents reflect his commitment to improving medical outcomes through advanced detection methods. His work continues to influence the landscape of medical research and diagnostics.