The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 12, 2018
Filed:
Oct. 02, 2015
Applicant:
Roche Molecular Systems, Inc., Pleasanton, CA (US);
Inventors:
Bryan Hoglund, Pleasanton, CA (US);
Janet Jin, Foster City, CA (US);
Yan Li, Palo Alto, CA (US);
Wei-Min Liu, Dublin, CA (US);
Assignee:
Roche Molecular Systems, Inc., Pleasanton, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12P 19/34 (2006.01); A61K 31/517 (2006.01); A61K 31/5377 (2006.01); C07K 16/28 (2006.01); C07K 16/32 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); A61K 31/517 (2013.01); A61K 31/5377 (2013.01); C07K 16/2863 (2013.01); C07K 16/32 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/156 (2013.01);
Abstract
A new in-frame deletion was found in exon 19 of the EGFR gene, the exon that is often mutated in tumors. The invention comprises methods of detecting the mutation, methods of prognosis and methods of predicting response to treatment based on the presence of absence of the mutation.