Location History:
- Grosseto, IT (2019 - 2020)
- Siena, IT (2023)
Company Filing History:
Years Active: 2019-2023
Title: Brunella Brunelli: Innovator in Meningococcal Vaccine Development
Introduction
Brunella Brunelli is a notable inventor based in Grosseto, Italy, recognized for her contributions to the field of vaccine development. With a total of three patents to her name, she has made significant strides in improving meningococcal vaccines.
Latest Patents
Brunelli's latest patents focus on enhancing the efficacy of meningococcal vaccines. One of her inventions proposes that meningococcal vaccines can be improved by including multiple alleles or variants of fHbp. This approach aims to provide broader coverage of the diversity known for this protein. Additionally, she has developed adjuvanted combinations of meningococcal factor H binding proteins. This invention addresses the poor coverage of the M01573 sequence in vaccines by incorporating two family I fHbp sequences, one closely related to MC58 and the other to M01573. Furthermore, her multi-family fHbp-based vaccine combines a family I fHbp sequence with a family III fHbp sequence, all adjuvanted with aluminium phosphate.
Career Highlights
Brunelli is currently associated with GlaxoSmithKline Biologicals SA, where she continues her research and development efforts in vaccine technology. Her work has been pivotal in advancing the understanding and effectiveness of meningococcal vaccines.
Collaborations
Brunelli collaborates with esteemed colleagues such as Maurizio Comanducci and Mariagrazia Pizza, who contribute to her research endeavors and the development of innovative vaccine solutions.
Conclusion
Brunella Brunelli's work in the field of meningococcal vaccines exemplifies her commitment to improving public health through innovation. Her patents reflect a deep understanding of vaccine technology and a dedication to addressing critical health challenges.