Company Filing History:
3 out of 16,338 
2 out of 206 Years Active: 1986-1996
Title: Bruce J Aungst: Innovator in Pharmaceutical Formulations
Introduction
Bruce J Aungst is a notable inventor based in Wilmington, DE (US). He has made significant contributions to the field of pharmaceutical formulations, holding a total of 5 patents. His work focuses on developing innovative compositions that enhance the delivery and efficacy of various compounds.
Latest Patents
Among his latest patents, Aungst has developed pharmaceutical formulations of cyclic urea type compounds. These compositions comprise a cyclic urea type compound in a liquid or solid vehicle, which includes a fatty acid ester of glycerol or polyethylene glycol. The vehicle is designed to have a hydrophil-lipophil balance of at least about 10, optionally including other excipients. These formulations are particularly useful for providing good systemic absorption of cyclic urea compounds when administered enterally, especially orally. Additionally, he has created topical anti-inflammatory compositions that demonstrate minimal systemic absorption. These formulations utilize polyethylene glycol for the delivery of 2-substituted-1-naphthols and indoles, specifically 2-phenylmethyl-1-naphthol. They exhibit excellent localized anti-inflammatory activity while minimizing skin penetration, thereby reducing unwanted side effects and systemic toxicity.
Career Highlights
Throughout his career, Bruce J Aungst has worked with prominent companies such as E.I. du Pont de Nemours and Company and The DuPont Merck Pharmaceutical Company. His experience in these organizations has allowed him to contribute to significant advancements in pharmaceutical science.
Collaborations
Aungst has collaborated with notable colleagues, including Munir A Hussain and Robert C DiLuccio. These partnerships have further enriched his research and development efforts in the pharmaceutical field.
Conclusion
Bruce J Aungst is a distinguished inventor whose work in pharmaceutical formulations has made a lasting impact. His innovative approaches to drug delivery continue to advance the field and improve treatment options for various conditions.