Brooke Hjelm

Title: Brooke Hjelm: Innovator in Plant-Based Vaccine Production

Introduction

Brooke Hjelm is a prominent inventor based in Tempe, AZ (US), known for her groundbreaking work in the field of biotechnology. She has made significant contributions to the development of innovative systems for the rapid production of vaccines and monoclonal antibody therapeutics using plant viral vectors. With a total of 2 patents, her work is paving the way for advancements in medical biotechnology.

Latest Patents

One of her latest patents is a DNA replicon system designed for high-level rapid production of vaccines and monoclonal antibody therapeutics in plants. This innovative system utilizes a geminivirus-based approach to achieve high-yield and rapid production of oligomeric protein complexes, including virus-like particle (VLP) vaccines and monoclonal antibodies (mAbs). The patent describes a single vector that contains two non-competing replicons for transient expression in plant leaves. This advancement eliminates the need for non-competing viruses, enhancing the commercial application of plant transient expression technology for producing multiple-subunit protein complexes.

Career Highlights

Brooke Hjelm is affiliated with Arizona State University, where she continues to push the boundaries of research in plant-based biotechnology. Her work has garnered attention for its potential to revolutionize the production of essential medical therapeutics.

Collaborations

Some of her notable coworkers include Hugh S Mason and Zhong Huang, who have collaborated with her on various research projects aimed at enhancing the efficacy of plant-based production systems.

Conclusion

Brooke Hjelm's innovative contributions to the field of biotechnology, particularly in the area of plant-based vaccine production, highlight her role as a leading inventor. Her work not only advances scientific knowledge but also holds promise for future medical applications.