The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 29, 2016
Filed:
Jul. 17, 2013
The Arizona Board of Regents for and on Behalf of Arizona State University, Tempe, AZ (US);
Hugh S Mason, Phoenix, AZ (US);
Zhong Huang, Tempe, AZ (US);
Qiang Chen, Chandler, AZ (US);
Charles J Arntzen, Gold Canyon, AZ (US);
Shuo Yuan, Tempe, AZ (US);
Brooke Hjelm, Tempe, AZ (US);
Arizona Board of Regents on behalf of Arizona State University, Tempe, AZ (US);
Abstract
Plant viral vectors have great potential in rapid production of proteins, but no simple Here a geminivirus-based system for high-yield and rapid production of oligomeric protein complexes, including virus-like particle (VLP) vaccines and monoclonal antibodies (mAbs) is described. In particular, a single vector that contains two non-competing replicons for transient expression inleaves is described. The correct assembly of these subunit proteins into functional oligomeric structures (VLPs or full-size mAb) is also described. This system advances plant transient expression technology by eliminating the need for non-competing viruses, and thus, enhances the realistic commercial application of this technology for producing multiple-subunit protein complexes.