Brooke Harrison

Title: Brooke Harrison: Innovator in Cardiac Treatment

Introduction

Brooke Harrison is a prominent inventor based in Longmont, CO (US). She has made significant contributions to the field of cardiac treatment through her innovative research and patents. Her work focuses on the interactions of CaMKII with HDACs and calpain, which are crucial in understanding heart diseases.

Latest Patents

Brooke Harrison holds 1 patent titled "Methods of treatment and uses for CaMKII and its interaction with HDACs and calpain." This invention provides methods for treating cardiac hypertrophy, heart failure, dilated cardiomyopathy, or hypertension by utilizing CaMKII-HDAC binding domains. The patent reveals that CaMKII binds to HDAC4 at a specific site, leading to the dimerization of HDAC4 with other HDACs. This process can result in the export of HDACs from the nucleus to the cytoplasm, which is associated with the development of heart disease. The methods outlined in her patent represent novel approaches to prevent, treat, or identify therapies for these serious cardiac conditions.

Career Highlights

Throughout her career, Brooke has worked with esteemed organizations such as the University of Texas System and Gilead Sciences, Inc. Her experience in these institutions has allowed her to collaborate with leading experts in the field and contribute to groundbreaking research.

Collaborations

Some of her notable coworkers include Johannes Backs and Khai Huynh. Their collaborative efforts have further advanced the understanding of cardiac diseases and potential treatments.

Conclusion

Brooke Harrison's innovative work in cardiac treatment exemplifies the impact of research and patents in advancing medical science. Her contributions are vital in the ongoing fight against heart disease, showcasing the importance of innovation in healthcare.