Brian W Matthews

Title: Brian W Matthews: Innovator in Xylose Isomerase Research

Introduction

Brian W Matthews is a notable inventor based in Eugene, OR (US). He has made significant contributions to the field of biochemistry, particularly in the development of xylose isomerase muteins. His work has implications for the conversion of glucose to fructose, which is vital in various industrial applications.

Latest Patents

Matthews holds a patent for "Procaryotic xylose isomerase muteins." This patent describes the methods for obtaining xylose isomerase muteins that are useful in the conversion of glucose to fructose or xylose to xylulose. The techniques employed include protein structural methods and recombinant DNA methods, such as x-ray crystallography, cloning, computer graphic modeling, and site-directed mutagenesis. The native bacterial DNA sequences encoding procaryotic xylose isomerase are altered to enhance catalytic function and thermostability. He has 1 patent to his name.

Career Highlights

Throughout his career, Matthews has worked with prominent organizations, including Cetus Corporation and the University of Oregon. His experience in these institutions has allowed him to advance his research and contribute to the scientific community.

Collaborations

Matthews has collaborated with several notable individuals in his field, including Pamela L Toy and Will Bloch. These collaborations have enriched his research and expanded the impact of his work.

Conclusion

Brian W Matthews is a distinguished inventor whose work in xylose isomerase research has paved the way for advancements in biochemistry. His innovative approaches and collaborations continue to influence the field significantly.