The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 20, 1991
Filed:
Aug. 11, 1987
Applicant:
Inventors:
Robert J Drummond, Richmond, CA (US);
Will Bloch, El Cerrito, CA (US);
Brian W Matthews, Eugene, OR (US);
Pamela L Toy, Oakland, CA (US);
Assignees:
Cetus Corporation, Emeryville, CA (US);
Univerity of Oregon, Eugene, OR (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435234 ; 435 691 ; 435 712 ; 435 91 ; 435169 ; 4351723 ; 4352523 ; 4353201 ; 435886 ; 536 27 ; 935 14 ; 935 29 ; 935 61 ; 935 72 ;
Abstract
Xylose isomerase (XI) muteins useful in the conversion of glucose to fructose or xylose to xylulose are obtained in usable amounts by protein structural and recombinant DNA methods, including x-ray crystallography, cloning, computer graphic modeling and site-directed mutagenesis and expression of the bacterial DNA sequences encoding native procaryotic xylose isomerase. These native sequences are altered to encode the xylose isomerase muteins having improved catalytic function and/or thermostability.