Company Filing History:
Years Active: 2018-2021
Title: Innovations in Cancer Treatment by Brian Van Tine
Introduction
Brian Van Tine is a notable inventor based in St. Louis, MO (US), recognized for his significant contributions to cancer research and treatment. With a total of four patents to his name, he has developed innovative methods that aim to improve the diagnosis and treatment of various cancers.
Latest Patents
One of his latest patents is focused on methods of diagnosing and treating cancer that involve the malic enzyme 1 (ME1). This patent outlines a method for determining treatment options for cancer by identifying the absence of ME1 and utilizing an inducer of ferroptosis. Another significant patent involves sigma-2 receptor ligand drug conjugates as antitumor compounds. This patent describes methods and compositions for treating cancers, including pancreatic cancer and synovial sarcoma. The compounds detailed in this patent exhibit promising results, with at least one molecular species showing an IC value below 5 µM against human pancreatic cancer cells in vitro. Furthermore, the administration of this species has demonstrated the ability to promote tumor shrinkage in a murine model, leading to a remarkable 100% survival rate in experimental animals, compared to only 30% or 40% survival with control therapies.
Career Highlights
Brian Van Tine is affiliated with Washington University, where he continues to advance his research in cancer treatment. His work has garnered attention for its potential to revolutionize therapeutic approaches to challenging cancers.
Collaborations
He has collaborated with esteemed colleagues, including William G Hawkins and Robert H Mach, contributing to the advancement of cancer research and treatment methodologies.
Conclusion
Brian Van Tine's innovative work in cancer treatment exemplifies the impact of research and invention in the medical field. His patents reflect a commitment to improving patient outcomes and advancing scientific knowledge in oncology.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.