The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 09, 2019

Filed:

Aug. 24, 2018
Applicant:

Washington University, St. Louis, MO (US);

Inventors:

William Hawkins, St. Louis, MO (US);

Robert Mach, St. Louis, MO (US);

Dirk Spitzer, St. Louis, MO (US);

Suwanna Vangveravong, St. Louis, MO (US);

Brian Van Tine, St. Louis, MO (US);

Assignee:

Washington University, St. Louis, MO (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 451/14 (2006.01); C07D 471/08 (2006.01); A61K 31/496 (2006.01); A61K 31/517 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 451/14 (2013.01); A61K 31/496 (2013.01); A61K 31/517 (2013.01); A61K 45/06 (2013.01); C07D 471/08 (2013.01);
Abstract

The present disclosure provides compounds of structural Formula III: or a salt thereof, wherein Y is chosen from Further provided are pharmaceutical compositions comprising these compounds, and methods for treating cancer, such as pancreatic cancer or synovial sarcoma, using the compounds and compositions.


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