Location History:
- Hummelstown, PA (US) (2014)
- Elizabethtown, PA (US) (2015)
Company Filing History:
Years Active: 2014-2015
Title: Innovations by Brian M Barth
Introduction
Brian M Barth is an accomplished inventor based in Elizabethtown, PA (US). He holds 2 patents that focus on advanced biomedical applications. His work primarily revolves around the development of innovative nanoparticle technologies for targeted drug delivery and imaging.
Latest Patents
One of his latest patents is titled "Bioconjugation of calcium phosphosilicate nanoparticles for selective targeting of cells in vivo." This invention involves non-aggregating resorbable calcium phosphosilicate nanoparticles (CPNPs) that are bioconjugated to targeting molecules specific for particular cells. The CPNPs are stable at normal physiological pH, allowing for the compartmentalization of chemotherapy and imaging agents within the nanoparticles. This method ensures that the agents are protected from environmental interactions until they are taken up by the target cells, where they are released at intracellular pH. This innovative approach limits systemic exposure while delivering a higher concentration of agents directly to the cells.
Another significant patent by Barth is "In vivo photodynamic therapy of cancer via a near infrared agent encapsulated in calcium phosphate nanoparticles." This invention describes the use of nano-encapsulated photosensitizers for tumor treatment and imaging. By encapsulating the photosensitizers in calcium phosphate nanoparticles, the half-life and absorption of the agents into target tissues are significantly enhanced. This results in improved photostability and photoefficiency, making it a highly effective solution for photodynamic therapy and tumor detection.
Career Highlights
Brian M Barth is associated with the Penn State Research Foundation, where he contributes to cutting-edge research in nanotechnology and its applications in medicine. His work has the potential to revolutionize cancer treatment and improve patient outcomes through targeted therapies.
Collaborations
Throughout his career, Barth has collaborated with notable colleagues, including James H Adair and Mark Kester. These partnerships have fostered a collaborative environment that enhances the innovation process and leads to significant advancements in their field.
Conclusion
Brian M Barth's contributions to the field of biomedical engineering through his innovative patents demonstrate his commitment to advancing medical technology. His work in nanoparticle development is paving the way for more effective cancer treatments and improved imaging techniques.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.