Halifax, Canada

Brian Little

This inventor holds 1 USPTO granted patent and 1 published patent application. Top assignee: Dalhousie University. Active years: 2025.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Brian Little. Retrieved from https://idiyas.com/inventor/brian-little-hamr4ns3

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

USPTO Granted Patents = 1 

% Patents Active = 100.0

Average Co-Inventor Count = 4.0

ph-index = 1


Company Filing History:


Years Active: 2025

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1 patent (USPTO):Explore Patents

Title: Innovations in Radiotherapy: The Contributions of Brian Little

Introduction

Brian Little is an accomplished inventor based in Halifax, Canada. He has made significant contributions to the field of radiotherapy through his innovative patent. His work focuses on improving the planning and delivery of radiation treatment, which is crucial for effective cancer care.

Latest Patents

Brian Little holds a patent for "Systems and methods for planning, controlling and/or delivering radiotherapy and radiosurgery using combined optimization of dynamic axes (CODA)." This patent describes methods and systems for radiation treatment planning and delivery that utilize a CODA cube. The cost values in the CODA cube are instrumental in optimizing couch, collimator, and gantry angles simultaneously. The trajectories generated using the CODA cube demonstrate significant advantages over conventional Volumetric Modulated Arc Therapy (VMAT). Notably, a statistically significant sparing of Organ at Risk (OAR) maximum radiation doses was observed. CODA plans resulted in a reduction of maximum radiation dose in OARs by 20.6% (p<0.01), with the maximum brainstem radiation dose decreased by 2.63 Gy (p=0.031) on average. Additionally, there was a mean reduction in total Monitor Units (MU) of 8.6% (p=0.156), and a mean decrease in non-target brain tissue receiving 12 Gy or higher of 3.9% (p=0.16) when compared to standard VMAT methods.

Career Highlights

Brian Little is affiliated with Dalhousie University, where he continues to advance research in radiotherapy. His innovative approaches have garnered attention in the medical community, contributing to improved patient outcomes in cancer treatment.

Collaborations

Brian has collaborated with notable colleagues, including Robert Lee MacDonald and Alasdair Syme. Their combined expertise enhances the research and development of advanced radiotherapy techniques.

Conclusion

Brian Little's contributions to the field of radiotherapy through his innovative patent demonstrate the potential for improved cancer treatment methodologies. His work not only advances technology but also significantly impacts patient care.

Profile summary based on public USPTO records.
Data Sources: USPTO Patent Grant XML, Patent Center, EPO & CIPO • Normalized by IDiyas Innovation Graph. Methodology & provenance architecturePlease report any incorrect information to [email protected]
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