The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 01, 2025

Filed:

Apr. 18, 2019
Applicant:

Dalhousie University, Halifax, CA;

Inventors:

Robert Lee MacDonald, Antigonish, CA;

Alasdair Syme, Halifax, CA;

Christopher G. Thomas, Halifax, CA;

Brian Little, Halifax, CA;

Assignee:

Dalhousie University, Halifax, CA;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61N 5/10 (2006.01); G16H 10/60 (2018.01); G16H 20/40 (2018.01); G16H 50/70 (2018.01);
U.S. Cl.
CPC ...
A61N 5/1037 (2013.01); A61N 5/1045 (2013.01); A61N 5/1081 (2013.01); G16H 10/60 (2018.01); G16H 20/40 (2018.01); G16H 50/70 (2018.01);
Abstract

Methods and systems for radiation treatment planning and delivery apply a CODA cube. Cost values in the CODA cube may be used in the optimization of couch, collimator, and gantry angles simultaneously. Trajectories generated using the CODA cube show significant benefits when compared to conventional VMAT. A statistically significant sparing to OAR maximum radiation doses was seen. CODA plans resulted in a reduction to maximum radiation dose in OARs of 20.6% (p<0.01), with maximum brainstem radiation dose decreased by 2.63 Gy (p=0.031) on average. Mean reduction in total MU was 8.6% (p=0.156), and a mean decrease in non-target brain tissue receiving 12 Gy or higher was 3.9% (p=0.16), when compared to standard VMAT methods (n=7).


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