Company Filing History:
Years Active: 2003-2006
Title: Brian Johnstone: Innovator in Pharmacogenomics
Introduction
Brian Johnstone is a notable inventor based in Benicia, CA (US). He has made significant contributions to the field of pharmacogenomics, focusing on methods that enhance our understanding of drug interactions and their effects on cellular mechanisms. With a total of 3 patents, Johnstone's work is paving the way for advancements in personalized medicine.
Latest Patents
Johnstone's latest patents include innovative screening methods that isolate a collection of polynucleotides corresponding to accessible regions of chromatin. These methods assess potential pharmacological effects and/or side effects of agents based on their impact on the distribution and properties of accessible regions in cellular chromatin. Additionally, he has developed methods for identifying drug targets by reconstructing signal transduction pathways based on sequences of accessible regions. This involves selecting a gene of therapeutic interest and determining the regulatory DNA sequences that control its expression in specific cells. His work is crucial for understanding how agents affect cellular processes and for identifying new therapeutic targets.
Career Highlights
Johnstone is currently associated with Sangamo Biosciences, Inc., where he continues to innovate in the field of genetic research and drug development. His expertise in pharmacogenomics has positioned him as a key player in the advancement of personalized medicine.
Collaborations
Some of his notable coworkers include Alan P. Wolffe and Fyodor Urnov, who have collaborated with him on various projects aimed at enhancing drug development processes.
Conclusion
Brian Johnstone's contributions to pharmacogenomics and his innovative patents are instrumental in advancing our understanding of drug interactions and therapeutic targets. His work continues to influence the field and holds promise for future medical advancements.