Company Filing History:
Years Active: 1998-2008
Title: Brian James Hicke: Innovator in Nucleic Acid Ligands
Introduction
Brian James Hicke is a notable inventor based in Boulder, CO (US). He has made significant contributions to the field of nucleic acid ligands, holding a total of 10 patents. His work focuses on developing high-affinity ligands that have important applications in medical diagnostics and therapeutics.
Latest Patents
One of his latest patents is titled "High Affinity Nucleic Acid Ligands to Lectins." This invention discloses high-affinity oligonucleotide ligands to lectins, specifically nucleic acid ligands that can bind to wheat germ agglutinin, L-selectin, E-selectin, and P-selectin. The patent also includes methods for obtaining such ligands. Another significant patent is "Tenascin-C Nucleic Acid Ligands," which describes methods for identifying and preparing nucleic acid ligands to tenascin-C. This invention includes specific RNA ligands identified by the SELEX method and methods for detecting disease conditions in biological tissues where tenascin-C is expressed.
Career Highlights
Throughout his career, Brian has worked with prominent companies in the pharmaceutical and biotechnology sectors. He has been associated with Gilead Sciences, Inc. and Nexstar Pharmaceuticals, Inc., where he contributed to innovative research and development projects.
Collaborations
Brian has collaborated with esteemed colleagues, including David H Parma and Larry M Gold. Their combined expertise has further advanced the research in nucleic acid ligands and their applications.
Conclusion
Brian James Hicke is a distinguished inventor whose work in nucleic acid ligands has the potential to impact medical diagnostics and treatment. His innovative patents and collaborations highlight his significant contributions to the field.