Brian H Clare

Title: Innovations of Brian H Clare

Introduction

Brian H Clare is an accomplished inventor based in Madison, WI (US). He has made significant contributions to the field of biochemistry and molecular biology, holding a total of 4 patents. His work primarily focuses on the detection of post-translationally modified peptides and the use of liquid crystals in biomolecular detection.

Latest Patents

One of his latest patents is titled "Detection of post-translationally modified peptides with liquid crystals." This invention outlines a method for differentiating between a post-translationally modified peptide and a peptide contained in a sample. The process involves creating a peptidized surface by contacting the sample with a peptide attachment surface, followed by the use of a recognition reagent that selectively binds to the modified peptide. The final step includes detecting the presence of the modified peptide using liquid crystals.

Another notable patent is "Using liquid crystals to detect affinity microcontact printed biomolecules." This invention provides methods, devices, and kits for detecting a ligand. The methods involve capturing a ligand from a sample with an affinity substrate that includes a receptor for the ligand. The captured ligand is then transferred to a detection surface, where it is detected using liquid crystals, effectively decoupling the capture and detection steps.

Career Highlights

Brian H Clare is associated with the Wisconsin Alumni Research Foundation, where he continues to innovate and contribute to scientific advancements. His work has garnered attention for its practical applications in the detection of biomolecules, which is crucial for various research and clinical settings.

Collaborations

He has collaborated with notable colleagues, including Nicholas Lawrence Abbott and Paul J Bertics, further enhancing the impact of his research through teamwork and shared expertise.

Conclusion

Brian H Clare's innovative work in the field of biochemistry, particularly in the detection of modified peptides and the application of liquid crystals, showcases his significant contributions to science. His patents reflect a commitment to advancing technology in molecular detection, making a lasting impact in his field.