This inventor holds 8 USPTO granted patents and 9 published patent applications and 1 EPO patent. Top assignees: Orna Therapeutics, Inc., Renagade Therapeutics Management Inc., Massachusetts Institute of Technology. Active years: 2023-2025.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
6 out of 12 
2 out of 6 
1 out of 8,586 
Years Active: 2023-2025
Title: Brian Goodman: Innovator in Circular RNA Technology
Introduction
Brian Goodman is a prominent inventor based in Cambridge, MA (US). He has made significant contributions to the field of biotechnology, particularly in the development of circular RNA technologies. With a total of 8 patents to his name, Goodman is recognized for his innovative approaches to genetic engineering and therapeutic applications.
Latest Patents
One of Goodman's latest patents is titled "Circular RNA encoding chimeric antigen receptors targeting BCMA." This patent describes circular RNA along with related compositions and methods. In some embodiments, the inventive circular RNA comprises group I intron fragments, spacers, an IRES, duplex forming regions, and an expression sequence. The expression sequence encodes an antigen, and the circular RNA of the invention demonstrates improved expression, functional stability, immunogenicity, ease of manufacturing, and half-life compared to linear RNA. Additionally, the methods and constructs developed by Goodman result in enhanced circularization efficiency, splicing efficiency, and purity when compared to existing RNA circularization approaches.
Career Highlights
Goodman has worked with several notable companies in the biotechnology sector, including Orna Therapeutics, Inc. and Renagade Therapeutics Management Inc. His work has focused on advancing the understanding and application of RNA technologies in therapeutic contexts.
Collaborations
Throughout his career, Goodman has collaborated with esteemed colleagues such as Robert Alexander Wesselhoeft and Allen T Horhota. These collaborations have contributed to the advancement of his research and the successful development of innovative technologies.
Conclusion
Brian Goodman is a leading figure in the field of circular RNA technology, with a strong portfolio of patents that reflect his innovative spirit. His contributions continue to shape the landscape of biotechnology and genetic engineering.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile