The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 06, 2024
Filed:
Sep. 22, 2023
Applicant:
Renagade Therapeutics Management Inc., Cambridge, MA (US);
Inventors:
Alim Ladha, Cambridge, MA (US);
Vladimir Presnyak, Cambridge, MA (US);
Inna Shcherbakova, Cambridge, MA (US);
Brian Goodman, Cambridge, MA (US);
Mario Rodriguez Mestre, Cambridge, MA (US);
Devin Scott Quinlan, Cambridge, MA (US);
Muthusamy Jayaraman, Cambridge, MA (US);
Stephen Scully, Cambridge, MA (US);
Assignee:
RENAGADE THERAPEUTICS MANAGEMENT INC., Cambridge, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); C12N 9/12 (2006.01); C12N 15/11 (2006.01); C12N 15/90 (2006.01);
U.S. Cl.
CPC ...
C12N 15/907 (2013.01); C12N 9/1276 (2013.01); C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 2310/20 (2017.05); C12N 2310/531 (2013.01); C12N 2800/80 (2013.01);
Abstract
Disclosed are engineered retrons and methods of use such as to modify the genome of a host (e.g., mammalian) cell by delivering the engineered retron or the encoded ncRNA in vitro or in vivo to the host (e.g., mammalian) cell.