Wellesley, MA, United States of America

Brian Felice

USPTO Granted Patents = 2 

 

Average Co-Inventor Count = 4.7

ph-index = 2

Forward Citations = 9(Granted Patents)


Company Filing History:


Years Active: 2015-2017

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2 patents (USPTO):Explore Patents

Title: Brian Felice: Innovator in Lysosomal Enzyme Therapies

Introduction

Brian Felice is a notable inventor based in Wellesley, MA (US). He has made significant contributions to the field of medical therapies, particularly in the treatment of lysosomal storage diseases. With a total of 2 patents, his work focuses on innovative methods for enzyme replacement therapies.

Latest Patents

One of Brian Felice's latest patents is titled "Subcutaneous administration of iduronate-2-sulfatase." This invention provides compositions, kits, and methods for the subcutaneous delivery of lysosomal enzymes, which are crucial for the effective treatment of lysosomal storage diseases. The patent outlines methods for treating Hunter syndrome through the subcutaneous administration of a replacement iduronate-2-sulfatase (I2S) protein. Additionally, it includes a kit designed for the subcutaneous administration of I2S protein. Another significant patent is for "Methods for treating lysosomal acid lipase deficiency." This invention offers compositions and methods for treating lysosomal acid lipase deficiency (LALD) diseases, such as Wolman's disease and Cholesteryl Ester Storage Disease (CESD). It provides a method for treating developmental impairment or malnutrition in individuals suffering from LALD by administering a therapeutically effective amount of lysosomal acid lipase.

Career Highlights

Throughout his career, Brian Felice has worked with prominent companies in the biotechnology sector. He has been associated with Synageva Biopharma Corporation and Shire Human Genetic Therapies, Inc. These experiences have allowed him to contribute to the advancement of genetic therapies and innovative treatment solutions.

Collaborations

Brian has collaborated with notable professionals in his field, including Michael W Heartlein and Michael F Concino. These collaborations have further enriched his work and contributed to the development of effective therapies for lysosomal storage diseases.

Conclusion

Brian Felice is a distinguished inventor whose work in lysosomal enzyme therapies has the potential to significantly impact the treatment of rare genetic disorders. His innovative patents and collaborations highlight his commitment to advancing medical science and improving patient outcomes.

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